Anadrol (Oxymetholone)

Anadrol Oxymetholone


Anadrol Oxymetholone is the most powerful and popular mg to mg oral anabolic steroid in existence.  It has many unique features about it, which has to do with how it reacts in the body and how it was structured.  In this article we will discuss the best ways to utilize it to your advantage1

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History of Anadrol use

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Anadrol Oxymetholone first came to the market in 1961 in the United Kingdom as the brand name ‘Anapolon’. Syntex was the pharmaceutical company that branded it as ‘Anadrol’ and it was marketed and FDA approved throughout the 60s in the United States as a strong steroid for treating anemia.  It also was prescribed outside the USA for those who were malnourished and bone health.  Once drugs with less side effects came along it fell out of favor and then was mostly only used for HIV/AIDS patients2

In the bodybuilding world, athletes started using the steroid during the golden age and its popularity stayed constant into the 90’s and 2000’s as mass and size became more popular.  Today it is still used by those who want something to build a lot of mass and strength in a short period of time. 

Anadrol Structure

Oxymetholone side effects

Anadrol Oxymetholone is a DHT (dihydrotestosterone) derivative.  It has a 2-hydroxymethylene group making it more anabolic than other DHT’s in its class3

Since it is a DHT it will not aromatize into estrogen, however it can affect estrogen receptors where the user gets estrogenic side effects.  In theory, an aromatize inhibitor is useless with the steroid since it isn’t aromatizing in the first place, so some guys swear by using the SERM nolvadex while on it to combat those estrogenic issues.  In the end, it is a very risky steroid to use if you are prone to estrogenic problems due to how it is structured.

It also has a 17AA alteration which allows the steroid to survive liver passage, so expect some fast liver stress.

Bulking and strength

Anapolon results before and after

Anadrol Oxymetholone is great when it comes to quick mass building and fast strength gains.  It does a great job of boosting protein synthesis and boosting red blood cell count.  These combinations will allow you to get more out of your workout and reap the rewards.  It also is well known to increase appetite so you will be able to feed your muscles and not feel satiated as fast from a meal. 

One of the reasons people choose Anadrol Oxymetholone is that it can change your physique in a short time frame.  If you use it correctly, get a good workout program, eat muscle building foods and have a good mindset you can expect to look like a different person in under 6 weeks when running a cycle. 

You also will get some amazing pumps in the gym and leave feeling amazing like you just went to battle. 

Half-life of Anadrol

The half life is around 8 hours, so once or twice a day dosing is recommended.  

Detection times

The detection time is listed at 8 weeks and it is obviously banned by all sports leagues. 

Side effects of Anadrol

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Anadrol Oxymetholone has numerous side effects which are hard to combat when they get out of control.  The issues become complicated because it has 4 distinct features that give you side effects from a bunch of places you wouldn’t see from other steroids.

1.  Estrogenic: 

Although it is a DHT derivative, it still effects the estrogen receptors so you can still get problems with gynocomestia, bloat, high blood pressure, tiredness, and insomnia.

2.  Androgenic: 

Aggression, mood swings, impatience, heart strain, fatigue and insomnia are all common issues.

3.  DHT: 

Dihydrotestosterone (DHT) side effects can manifest itself by harming your prostate and by shedding head hair. 

4.  Liver toxic: 

To top things off it is liver toxic.  You should run N2guard to help with this issue. 

Anadrol Dosages in bodybuilding and stacking

Oxymetholone dosages

Anadrol Oxymetholone does not need to be stacked nor does it need to be ran at high dosages.  I have personally enjoyed using just 25mg a day for 4-6 weeks and got outstanding results.  Some guys will push the dosage up to 50mgs a day, which is considered the standard bodybuilding dosage, to see how they do then drop the dose down if needed.  There is no reason to run it higher than that unless you want to risk problems. 

Mass builder:

No oral out there is capable of putting on mass faster and moving the weight scale up in such a short time.  You can add 10, 15, or even 20 pounds in just 4-6 weeks. 


It is amazing for strength especially for people stuck at plateau’s.  I have used it to break a 6 month strength plateau. 


You can choose to use it for contest prep but you must already have experience to know how your body reacts and you must stop using it as you get near competition day. 

Use as a kickstart: 

If you choose to use it in a stack you will want to kickstart it along with a mild dosage of Testosterone, Primo, Equipoise, or another low side effect steroid.  I do not recommend using it with another harsh steroid or you will risk major problems. 

Female use

We do not recommend females go near Anadrol Oxymetholone due to its unpredictable and numerous side effects.

3 biggest myths about Anadrol Oxymetholone and what guys on forums are saying

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1.  You must use a testosterone base with Anadrol Oxymetholone:   Actually, it is perhaps the best steroid to use solo because it gives you results from all directions, so stacking can actually be counter productive in some sense.  Discuss here.  

2. Anadrol Oxymetholone cannot cause bloat:   Some may believe because it will not aromatize, it cannot bloat.  As discussed earlier this is a wrong theory.  Discuss here.

3.  Anadrol Oxymetholone does not cause hair shedding:  On the flip side guys might not understand that it is a DHT derivative and think it doesn’t cause hair shedding, it actually will.  Discuss here.

Anadrol-Oxymetholone is a cheap steroid for 2 main reasons.  First, the raws are cheap and it is easy to produce. Second, you get a lot of bang for your buck with a small amount unlike other steroids.  You can run a cycle of it for $100 or less, plus likely have enough left over to use on a next cycle.  Every source out there carries it. 

There are 5 brands that we recommend that shine well. 

  • Zhengzhou Pharmaceuticals (ZPHC)
  • Balkan Pharmaceuticals
  • Pharmacom Labs
  • Alpha Pharma healthcare
  • Abdi Ibrahim
  1. Anadrol-50_PI.pdf retrieved from []
  2. Steroids. CVI.1 Synthesis of 7β-Methyl Hormone Analogs by John A. Zderic, Humberto Carpio, and H. J. Ringold []
  3. Pharmacology of anabolic steroids by A T Kicman []
About author


Steve Smi is a former competitive endurance athlete and powerlifter. He has been weight training for over 25 years and studied PED's for more than 15 years. He moderates 4 fitness forums, has written over 1000 articles, published over 4 books, and has interviewed Mr. Olympia Champions, including Frank Zane, in his over 400 published podcasts. In his spare time, he enjoys gardening, family, fishing, movies, and the outdoors. He is an advocate of giving back to the fitness community and sharing knowledge so everyone can better themselves. Ask Steve a question here.

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